Exome sequencing identifies a novel mutation in the MYH6 gene in a family with early-onset sinus node dysfunction, ventricular arrhythmias, and cardiac arrest☆

Lien Lam, BSc, PhD, Jodie Ingles, BBiomed Sci, PhD, MPH, Christian Turner, MBBS, Michael Kilborn, MBBS, PhD, Richard D. Bagnall, BSc, PhD, Christopher Semsarian, MBBS, PhD, MPH, FHRS From the Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, New South Wales, Australia, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia, The Heart Centre for Children, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia, and Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.